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PFO Closure

Patent foramen ovale (PFO) is an embryonic defect, seen in up to 25% of adults,¹ that has been associated with increased risk of ischemic stroke of unknown cause. It is defined as an opening in the septum between the atria that acts as a conduit for emboli from the deep veins of the pelvis or legs to the brain. Closure of a PFO may prevent paradoxical embolus from passing through a PFO and thereby reduce the risk of recurrent stroke.

Patent foramen ovale closure with the PFO Occluder

PFO closure is a same-day, outpatient procedure performed under general anesthesia or conscious sedation in a heart catheterization laboratory. The catheter-based procedure involves making a very small skin incision, guided by fluoroscopy and intracardiac echocardiography, typically in the right groin area, and inserting a catheter to guide the Amplatzer™ Talisman™ PFO Occluder through the blood vessels to close the PFO within the patient’s heart.

Over 180k patients treated for PFO

#1 Device Selected for PFO Closure

The Amplatzer™ Talisman™ PFO Occluder is built off a legacy of excellence, with over 20 years as the pioneer in PFO closure to reduce the risk of recurrent ischemic stroke. More than 180,000 patients have been treated worldwide.

  1. Kent DM, Thaler DE. Is patent foramen ovale a modifiable risk factor for stroke recurrence? Stroke. 2010;41(10 Suppl):S26-30. doi: 10.1161/STROKEAHA.110.595140
  2. Data on file at Abbott.
MAT-2003153 v3.0 | Item approved for U.S. use only.