About 1 in 4 people have a hole in their heart called a PFO¹
Before birth, all babies have a hole in the heart called the foramen ovale. This hole allows babies to get blood and oxygen through the umbilical cord. The foramen ovale normally closes after birth. In about 25% of people, this hole doesn’t close all the way.¹ When the hole remains open, it’s called a patent foramen ovale, or a PFO.