PFO closure is a same-day, outpatient procedure performed under general anesthesia or conscious sedation in a heart catheterization laboratory. The catheter-based procedure involves making a very small skin incision, guided by fluoroscopy and intracardiac echocardiography, typically in the right groin area, and inserting a catheter to guide the Amplatzer™ Talisman™ PFO Occluder through the blood vessels to close the PFO within the patient’s heart.
Patent foramen ovale (PFO) is an embryonic defect, seen in up to 25% of adults,¹ that has been associated with increased risk of ischemic stroke of unknown cause. It is defined as an opening in the septum between the atria that acts as a conduit for emboli from the deep veins of the pelvis or legs to the brain. Closure of a PFO may prevent paradoxical embolus from passing through a PFO and thereby reduce the risk of recurrent stroke.
#1 Device Selected for PFO Closure
The Amplatzer™ Talisman™ PFO Occluder is built off a legacy of excellence, with over 20 years as the pioneer in PFO closure to reduce the risk of recurrent ischemic stroke. More than 180,000 patients have been treated worldwide.
- Kent DM, Thaler DE. Is patent foramen ovale a modifiable risk factor for stroke recurrence? Stroke. 2010;41(10 Suppl):S26-30. doi: 10.1161/STROKEAHA.110.595140
- Data on file at Abbott.